Instructed extinction in human fear conditioning: History, recent developments, and future directions

Instructed extinction is an experimental manipulation that involves informing participants after the acquisition of fear learning that the unconditional stimulus (US) will no longer be presented. It has been used as a laboratory analogue to assess the capacity of cognitive interventions to reduce experimentally induced fear. In this review, we examine and integrate research on instructed extinction and discuss its implications for clinical practice. Overall, the results suggest that instructed extinction reduces conditional fear responding and facilitates extinction learning, except when conditional stimulus valence is assessed as an index of fear or when fear is conditioned to images of animal fear-relevant stimuli (snakes and spiders) or with a very intense US. These exceptions highlight potential boundary conditions for the reliance on cognitive interventions when treating fear in clinical settings

Startle modulation and explicit valence evaluations dissociate during backward fear conditioning

Blink startle magnitude is linearly modulated by affect such that, relative to neutral stimuli, startle magnitude is inhibited during pleasant stimuli and potentiated during unpleasant stimuli. Andreatta, Mühlberger, Yarali, Gerber, and Pauli (2010), however, report a dissociation between startle modulation and explicit valence evaluations during backward conditioning, a procedure in which the unconditional stimulus precedes the conditional stimulus (CS). Relative to controls, startles elicited during the CS were inhibited, suggesting that the CS had acquired positive valence, but participants still evaluated the CS as unpleasant after the experiment. In Experiment 1, we aimed to replicate this dissociation using a trial-by-trial measure of CS valence to measure startle modulation and CS valence simultaneously during forward and backward differential fear conditioning. In Experiment 2, we examined whether early and late portions of the CS could acquire differential valence by presenting startle probes at early and late probe positions during the CS. In both experiments, the dissociation between startle modulation and explicit valence evaluations in backward conditioning replicated, with CS+ evaluated as less pleasant than CS-, but startles elicited during CS+ inhibited relative to CS-. In Experiment 2, we provide preliminary evidence that this inhibition was present early, but not late, during the CS+. The results replicate the dissociation between implicit and explicit CS valence reported by Andreatta et al. (2010) using a trial-by-trial measure of valence. We also provide preliminary evidence that this dissociation may occur because the implicit and explicit measures are recorded at different times during the CS presentation

When orienting and anticipation dissociate - a case for scoring electrodermal responses in multiple latency windows in studies of human fear conditioning

Electrodermal activity in studies of human fear conditioning is often scored by distinguishing two electrodermal responses occurring during the conditional stimulus–unconditional stimulus interval. These responses, known as first interval responding (FIR) and second interval responding (SIR), are reported to be differentially sensitive to the effects of orienting and anticipation. Recently, the FIR/SIR scoring convention has been questioned, with some arguing in favor of scoring a single response within the entire conditional stimulus–unconditional stimulus interval (entire interval responding, EIR). EIR can be advantageous in practical terms but may fail to capture experimental effects when manipulations produce dissociations between orienting and anticipation. As an illustration, we rescored the data reported by Luck and Lipp (2015b) using both FIR/SIR and EIR scoring techniques and provide evidence that the EIR scoring technique fails to detect the effects of instructed extinction, an experimental manipulation which produces a dissociation between orienting and anticipation. Thus, using a technique that scores electrodermal response indices of fear conditioning in multiple latency windows is recommended

The influence of contingency reversal instructions on electrodermal responding and conditional stimulus valence evaluations during differential fear conditioning

In differential fear conditioning, the instruction that the conditional stimulus (CS) will no longer be followed by the unconditional stimulus (US; instructed extinction) reduces differential physiological responding (expectancy learning) but leaves differential CS valence evaluations (evaluative learning) intact. This dissociation suggests that expectancy, but not evaluative learning, responds to contingency instructions. Alternatively, as instructed extinction removes the threat of receiving the US, this dissociation could be caused by a drop in participants' arousal levels which could render the physiological indices of fear learning less sensitive. To test this alternative explanation, we examined the impact of an instructed reversal manipulation on electrodermal responding and CS valence evaluations. After instructed reversal, electrodermal responses to CS+ decreased and electrodermal responses to CS- increased, in the instruction, but not in the control group. In addition, there was some evidence for an instruction dependent change in CS valence, however, this finding seems limited to changes in CS+ valence and possible explanations for this finding are discussed. Overall, the study confirms that the dissociation detected in instructed extinction studies is unlikely to be caused by a drop in the participants' arousal levels

Novelty-facilitated extinction and the reinstatement of conditional human fear

© 2018 Elsevier Ltd. Although contemporary treatments for anxiety disorders are very efficient in reducing anxiety, return of fear after successful treatment is common which signifies a need for interventions that have a more enduring outcome. A recent laboratory study suggested that novelty-facilitated extinction, a simple modification of standard extinction which involves presenting a novel non-aversive stimulus during extinction, prevents spontaneous recovery, one laboratory analogue of return of fear. The current study assessed whether novelty-facilitated extinction can also prevent reinstatement, a second laboratory analogue of return of fear. Following differential fear conditioning, one group of participants underwent standard extinction training whereas the second was presented with a novel tone after the conditional stimulus that previously predicted the aversive unconditional stimulus (US). Three presentations of the USs alone reinstated differential electrodermal fear responses after standard extinction, but not after novelty-facilitated extinction. Moreover, replicating previous findings, the extent of return of fear was correlated with self-reported intolerance of uncertainty after standard extinction, but not after novelty-facilitated extinction. These results support the proposal that novelty-facilitated extinction training can reduce the extent of return of fear

Visual search for emotional expressions: Effect of stimulus set on anger and happiness superiority

Prior reports of preferential detection of emotional expressions in visual search have yielded inconsistent results, even for face stimuli that avoid obvious expression-related perceptual confounds. The current study investigated inconsistent reports of anger and happiness superiority effects using face stimuli drawn from the same database. Experiment 1 excluded procedural differences as a potential factor, replicating a happiness superiority effect in a procedure that previously yielded an anger superiority effect. Experiments 2a and 2b confirmed that image colour or poser gender did not account for prior inconsistent findings. Experiments 3a and 3b identified stimulus set as the critical variable, revealing happiness or anger superiority effects for two partially overlapping sets of face stimuli. The current results highlight the critical role of stimulus selection for the observation of happiness or anger superiority effects in visual search even for face stimuli that avoid obvious expression related perceptual confounds and are drawn from a single database

The spider does not always win the fight for attention: Disengagement from threat is modulated by goal set

Stimulus-driven preferential attention to threat can be modulated by goal-driven attention. However, it remains unclear how this goal-driven modulation affects specific attentional components implied in threat interference. We hypothesise that goal-driven modulation most strongly impacts delayed disengagement from threat. A spatial cueing task was used that disentangles delayed disengagement from attentional capture by tightly manipulating the locus of attention at the time of target onset. Different top-down goals were induced by instructing participants to identify bird/fish targets (Experiment 1) or spider/cat targets (Experiment 2) among animal non-targets. Delayed disengagement from a non-target spider was observed only when the spider was part of the target set, not when it was task-irrelevant. This corroborates evidence that threat stimuli do not necessarily override goal-driven attentional control and that extended processing of threatening distractors is not obligatory

Emotional Expressions Reduce the Own-Age Bias

© 2018 American Psychological Association. We are better at recognizing faces of our own age group compared to faces of other age groups. It has been suggested that this own-age bias (OAB) might occur because of perceptual-expertise and/or social- cognitive mechanisms. Although there is evidence to suggest effects of perceptual-expertise, little research has explored the role of social- cognitive factors. To do so, we looked at how the presence of an emotional expression on the face changes the magnitude of the OAB. Across 3 experiments, young adult participants were presented with young and older adult faces to remember. Neutral faces were first presented alone (Experiment 1) to validate the proposed paradigm and then presented along with angry (Experiment 2) and sad or happy faces (Experiment 3). The presence of an emotional expression improved the recognition of older adult faces, reducing the OAB which was evident for neutral faces. These results support the involvement of social- cognitive factors in the OAB, suggesting that a perceptual-expertise account cannot fully explain this face recognition bias

Different Faces in the Crowd: A Happiness Superiority Effect for Schematic Faces in Heterogeneous Backgrounds

Recently, D.V. Becker, Anderson, Mortensen, Neufeld, and Neel (2011) proposed recommendations to avoid methodological confounds in visual search studies using emotional photographic faces. These confounds were argued to cause the frequently observed Anger Superiority Effect (ASE), the faster detection of angry than happy expressions, and conceal a true Happiness Superiority Effect (HSE). In Experiment 1, we applied these recommendations (for the first time) to visual search among schematic faces that previously had consistently yielded a robust ASE. Contrary to the prevailing literature, but consistent with D.V. Becker et al. (2011), we observed a HSE with schematic faces. The HSE with schematic faces was replicated in Experiments 2 and 3 using a similar method in discrimination tasks rather than fixed target searches. Experiment 4 isolated background heterogeneity as the key determinant leading to the HSE

Emotional expressions preferentially elicit implicit evaluations of faces also varying in race or age

Both facial cues of group membership (race, age, and sex) and emotional expressions can elicit implicitevaluations to guide subsequent social behavior. There is, however, little research addressing whethergroup membership cues or emotional expressions are more influential in the formation of implicitevaluations of faces when both cues are simultaneously present. The current study aimed to determinethis. Emotional expressions but not race or age cues elicited implicit evaluations in a series of affectivepriming tasks with emotional Caucasian and African faces (Experiments 1 and 2) and young and old faces (Experiment 3). Spontaneous evaluations of group membership cues of race and age only occurred when those cues were task relevant, suggesting the preferential influence of emotional expressions in the formation of implicit evaluations of others when cues of race or age are not salient. Implications for implicit prejudice, face perception, and person construal are discussed